First, Vegito extends his hand with his palm open, similar to the Big Bang Attack. However, Vegito instead fires an energy wave instead of an energy sphere, dealing a large amount of damage.
Vegito used this attack against Super Buu in their fight. After emerging from Super Buu's energy attack unharmed, Vegito sarcastically asked Super Buu where he was aiming at, saying his aim is lousy. Vegito then says he will show it how its done, and charges and fires the Big Bang Flash at him, reducing him to pieces. However, Super Buu regenerated and continued the fight.