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Bio-Broly uses this technique twice in the movie Dragon Ball Z: Bio-Broly; once against Android 18 and later against Lord Jaguar and Men-Men. After Goten left Trunks alone against Bio-Broly to save people from the Culture Fluid, Android 18 punches the Bio-Warrior in the face in an attempt to help Trunks and Bio-Broly responds by firing his Bio-Hyper Beam at her. Later, after Goten once again attempted to leave the battle and was hit by Bio-Broly's Mouth Energy Wave, Lord Jaguar asks Bio-Broly, who is now crushing Trunks, to stop his rampage and Bio-Broly responds with his Bio-Hyper Beam, destroying the stairs Jaguar and his cousin were on.