"Unleash a super-powered Ki Wave that fuses two techniques together! It's powerful, but also uses up a lot of Ki!"
First, Vegito puts both of his hands forward and then towards his side, combining the massive power of the Final Flash and the Super Kamehameha into one attack. Then, Vegito fires the attack, as it appears as a giant, blue energy wave (resembling the Super Kamehameha) with swirls of yellow ki (resembling the Final Flash), inflicting an enormous amount of damage.
Super Saiyan Blue Vegito uses this attack during his battle against Fusion Zamasu in Dragon Ball Super. As Fusion Zamasu grows more and more powerful due to his intense emotions, Vegito knocks Fusion Zamasu away and proceeds to finish him off with the Final Kamehameha. Fusion Zamasu emerges the attack unharmed and Vegito attacks him further, however he immediately defuses and Goku and Vegeta are then defeated. Having used the Final Kamehameha as Vegito left Goku and Vegeta too weak to transform into a Super Saiyan again.
It is one of Vegito's techniques in Dragon Ball Z: Hyper Dimension, Dragon Ball GT: Final Bout, Dragon Ball Z: Shin Budokai, Dragon Ball Z: Infinite World, Dragon Ball Z: Budokai Tenkaichi 3, Dragon Ball Z: Tenkaichi Tag Team, the Raging Blast series, Dragon Ball Z: Ultimate Tenkaichi, Dragon Ball Z For Kinect, Dragon Ball Xenoverse 2, and Super Dragon Ball Heroes. In the games, he holds it out like a Final Flash and moves it back like a Kamehameha, and then releases it in a golden-yellow colored beam (it is a blue and white color in the Raging Blast games and Dragon Ball Z: Ultimate Tenkaichi).
In Dragon Ball Xenoverse 2, the Final Kamehameha appears as one of Vegito's Ultimate Skills which the Future Warrior can obtain by purchasing it from the TP Medal Shop (which is open from Friday to Sunday). Though it is powerful, it uses up 5 Ki Bars to fire (in contrast both the Final Flash and Super Kamehameha only require 3 Ki Bars).
- When performing the attack in Dragon Ball GT: Final Bout, Vegito yells "O tsugi wa koitsu da! FINARU KAMEHAMEHA!" (Next one is this! Final Kamehameha!).