Run, Android 17! Piccolo's All-Or-Nothing Struggle! (逃げろ１７号！ピッコロ、懸命の抗戦 Nigero Jūnana-Gō! Pikkoro, Kenmei no Kōsen, lit. Run #17! Piccolo, A battle for life) is the seventy-fourth episode of Dragon Ball Z Kai. Its Japanese air date was September 26, 2010. Its American air date was July 20, 2011.
Piccolo informs Android 17 of Cell's quest to absorb him and Android 18 to achieve his perfect form. He warns 17 to run away, but he refuses to, leading Piccolo to try and fight Cell; however, Cell proves too powerful for him and ends up defeating him.
Meanwhile, Goku and Gohan are still waiting for Vegeta and Future Trunks to come out of the Hyperbolic Time Chamber. Gohan senses that Piccolo is in trouble and tries to rush down to help him, but Goku stops him, saying that he is not powerful enough.